MITOCHONDRIAL DIVISION INHIBITOR (MDIVI-1) INDUCES EXTRACELLULAR MATRIX (ECM)-DETACHMENT OF VIABLE BREAST CANCER CELLS BY A DRP1-INDEPENDENT MECHANISM

Abstract Increasing evidence supports the hypothesis that cancer progression is under mitochondrial control.Mitochondrial fission plays a pivotal role in the maintenance of cancer cell homeostasis.The inhibition of DRP1, the main regulator of mitochondrial fission, with the mitochondrial division Slings inhibitor (mdivi-1) had been associated with

The article examines the fundamental foundations of the European approach to the regulation of digital transformation and the creation of an ideological and theoretical basis for the legal support of digitalization of society Chopsticks in the European Union.The concept of digital humanism, which is gaining more and more popularity, is analyzed and

A new method for evaluating the bone status using the scattering parameter of hardness indexes (Weibull homogeneity coefficient m) is proposed.A comparative analysis of Football Pants the condition of the Chopsticks bone tissue of birds, depending on age, breed and calcium content, is conducted.It is established that the scattering degree of mechan

Background A few odontocetes (echolocating toothed cetaceans) have been able to independently colonize freshwater ecosystems.Although some extant species of delphinids (true dolphins) and phocoenids (porpoises) at least occasionally migrate upstream of large river systems, they have close relatives in fully marine regions.This contrasts with the th

Abstract K-singular value decomposition (K-SVD) is a frequently used dictionary learning (DL) algorithm that iteratively works between sparse coding and dictionary updating.The sparse coding process generates sparse coefficients for each training sample, and the sparse coefficients induce clustering features.In the applications like image processin